Both periodontal disease and CVDs are multifactorial diseases that have many comorbidities. They share many risk factors, and both intensify and are propagated by the patient’s inflammatory burden. Good oral health is integral to optimal overall health and quality of life.107 However, the interactions between systemic and oral health may not be the primary focus of physicians and other healthcare providers.108 Dental healthcare providers should be aware of the burden and risks of CVD and the risk factors that CVD conveys in the dental setting. When treating patients with CVDs in the oral health setting, the goals are to develop and implement preventative and therapeutic strategies that allow the patient to tolerate and benefit from dental care. While the available data suggests the risk in performing dental procedures in patients with CVD is low, assessment of patient-specific factors are necessary to provide optimal dental and cardiovascular care.106 Stratification of cardiac risk and oral disease burden as well as coordination between the oral health care team and the treating physician is critical to allow for optimal patient care. Periodontal disease and the inflammatory burden it creates should be discussed with patients who have cardiac risk factors. The use of advanced therapies and/or more stringent maintenance protocols to control the increased inflammatory load in patients with both CVD and periodontitis should be considered.